Drug interactions
Alpelisib + Hydrochlorothiazide-losartan
Severity: Minor
Alpelisib and Hydrochlorothiazide-losartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alpelisib may induce CYP2C9, which converts losartan to its more potent active metabolite.
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Other interactions of Hydrochlorothiazide-losartan
Other interactions of Alpelisib
- Alpelisib + Carbamazepine Major
- Alpelisib + Phenytoin Major
- Alpelisib + Secobarbital Major
Drug class
- Alpelisib
- Oncology
- Hydrochlorothiazide-losartan
- Cardiovascular
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