Drug reference

hydrochlorothiazide-losartan

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Cardiovascular (Combination(CVS))

Mechanism of action

ARBs: Blocks binding of angiotensin II to type 1 angiotensin II receptors; blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II. Hydrochlorothiazide: Thiazide diuretic; inhibits sodium reabsorption in distal renal tubules.

Common side effects

  • URI
  • Fatigue
  • Chest pain
  • Hypotension
  • Cough
  • Hypoglycemia
  • Diarrhea

Known interactions (1)

Related conditions

Frequently asked questions

What drug class is hydrochlorothiazide-losartan?

hydrochlorothiazide-losartan belongs to: Cardiovascular.

How does hydrochlorothiazide-losartan work?

ARBs: Blocks binding of angiotensin II to type 1 angiotensin II receptors; blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II. Hydrochlorothiazide: Thiazide diuretic; inhibits sodium reabsorption in distal renal tubules.

What are the common side effects of hydrochlorothiazide-losartan?

URI, Fatigue, Chest pain, Hypotension, Cough, Hypoglycemia, Diarrhea

Which drugs interact with hydrochlorothiazide-losartan?

isocarboxazid

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