Drug interactions
Alpelisib + Losartan
Severity: Minor
Alpelisib and Losartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alpelisib may induce CYP2C9, the enzyme that converts losartan to its more potent active metabolite.
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Other interactions of Losartan
- Aliskiren + Losartan Contraindicated
- Amifostine + Losartan Major
- Amiloride + Losartan Major
Other interactions of Alpelisib
- Alpelisib + Carbamazepine Major
- Alpelisib + Phenytoin Major
- Alpelisib + Secobarbital Major
Drug class
- Alpelisib
- Oncology
- Losartan
- Cardiovascular
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