Drug reference
losartan
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (ARBs)
Mechanism of action
Blocks binding of angiotensin II to type 1 angiotensin II receptors; blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II
Common side effects
- Upper respiratory tract infection
- Anemia
- Dizziness
- Back pain
- Cough
- Nasal congestion
Boxed warnings
- Discontinue as soon as possible when pregnancy is detected; drug affects renin-angiotensin system, causing oligohydramnios, which may result in fetal injury or death (see Pregnancy & Lactation)
Contraindications
- Hypersensitivity Coadministration with aliskiren in patients with diabetes mellitus
Known interactions (3)
- Amlodipine/Atenolol + losartan Moderate
- Bumetanide + losartan Moderate
- losartan + Nitroglycerin Moderate
Related conditions
Frequently asked questions
What drug class is losartan?
losartan belongs to: Cardiovascular.
How does losartan work?
Blocks binding of angiotensin II to type 1 angiotensin II receptors; blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II
What are the common side effects of losartan?
Upper respiratory tract infection, Anemia, Dizziness, Back pain, Cough, Nasal congestion
Which drugs interact with losartan?
Amlodipine/Atenolol, Bumetanide, Nitroglycerin
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