Drug interactions
Alpelisib + Regorafenib
Severity: Moderate
Alpelisib and Regorafenib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Regorafenib may inhibit BCRP and could increase alpelisib exposure, potentially worsening hyperglycemia, rash, and diarrhea.
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Other interactions of Alpelisib
- Alpelisib + Carbamazepine Major
- Alpelisib + Phenytoin Major
- Alpelisib + Secobarbital Major
Drug class
- Alpelisib
- Oncology
- Regorafenib
- Oncology
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