Drug interactions
Alpelisib + Rolapitant
Severity: Moderate
Alpelisib and Rolapitant: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rolapitant inhibits BCRP, and alpelisib is a BCRP substrate, so alpelisib exposure may increase.
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Other interactions of Alpelisib
- Alpelisib + Carbamazepine Major
- Alpelisib + Phenytoin Major
- Alpelisib + Secobarbital Major
Drug class
- Alpelisib
- Oncology
- Rolapitant
- Gastrointestinal Tract
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