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Drug interactions

Alpelisib + Siponimod

Severity: Minor

Alpelisib and Siponimod: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Siponimod is metabolised mainly by CYP2C9, and alpelisib is a weak CYP2C9 inducer.

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Drug class

Alpelisib
Oncology
Siponimod
Central Nervous System

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