Drug reference
siponimod
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (MS Drugs)
Mechanism of action
Sphingosine-1-phosphate (S1P) receptor modulator, Binds with high affinity to S1P receptors 1 and 5; blocks lymphocyte egress from lymph nodes, reducing the number of lymphocytes in peripheral blood, Mechanism by which siponimod exerts therapeutic effects in MS is unknown, but may involve reduction of lymphocyte migration into the CNS
Common side effects
- Dizziness
- Headache
- Nausea
- Hypotension
- Transaminase increased
- Falls
- Peripheral edema
Related conditions
Frequently asked questions
What drug class is siponimod?
siponimod belongs to: Central Nervous System.
How does siponimod work?
Sphingosine-1-phosphate (S1P) receptor modulator, Binds with high affinity to S1P receptors 1 and 5; blocks lymphocyte egress from lymph nodes, reducing the number of lymphocytes in peripheral blood, Mechanism by which siponimod exerts therapeutic effects in MS is unknown, but may involve reduction of lymphocyte migration into the CNS
What are the common side effects of siponimod?
Dizziness, Headache, Nausea, Hypotension, Transaminase increased, Falls, Peripheral edema
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