Drug interactions
Alprazolam + Diphenoxylate
Severity: Moderate
Alprazolam and Diphenoxylate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Diphenoxylate is an opioid antidiarrheal, and combined use with alprazolam can increase sedation and CNS depression.
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Other interactions of Alprazolam
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