Skip to content

Drug interactions

Alprazolam + Lonafarnib

Severity: Major

Alprazolam and Lonafarnib: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Lonafarnib is a strong CYP3A inhibitor and can substantially increase alprazolam exposure, causing excessive sedation.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to see why Alprazolam and Lonafarnib interact, what to do about it, and the sources.

  • Mechanism of action
  • Clinical management
  • Evidence level

Try Pro+ free for 14 days on the web. No card needed.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in