Drug interactions
Alprazolam + Propofol
Severity: Major
Alprazolam and Propofol: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Benzodiazepines reduce the propofol dose needed for sedation or anesthesia, and together they increase the risk of deep sedation, hypotension, apnea and airway obstruction.
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Alprazolam and Propofol interact, what to do about it, and the sources.
- Mechanism of action
- Clinical management
- Evidence level
Free 14-day trial. No card needed.
Other interactions of Alprazolam
Other interactions of Propofol
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
