Drug interactions
Amantadine + Iloprost
Severity: Minor
Amantadine and Iloprost: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloprost is a potent vasodilator that lowers blood pressure. Amantadine can cause orthostatic hypotension, so the combination may add to hypotensive effects.
What this interaction means in plain words
Amantadine and Iloprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amantadine belongs to Anti Virals; Iloprost belongs to Cardiovascular.
Why it happens
Additive hypotensive effects through pharmacodynamic synergism.
What to do
Monitor blood pressure, especially when starting or increasing iloprost. Reduce the iloprost dose if symptomatic hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amantadine
- Amantadine + Ethanol Major
- Amantadine + Memantine-donepezil Major
- Amantadine + Metoclopramide Major
- Amantadine + Metoclopramide intranasal Major
- Amantadine + Amifampridine Moderate
- Amantadine + Amisulpride Moderate
Other interactions of Iloprost
- Aldesleukin + Iloprost Moderate
Frequently asked questions
Can I take Amantadine with Iloprost?
MediHelp rates the interaction as minor. Amantadine and Iloprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Iloprost is a potent vasodilator that lowers blood pressure. Amantadine can cause orthostatic hypotension, so the combination may add to hypotensive effects.
How serious is the interaction between Amantadine and Iloprost?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, especially when starting or increasing iloprost. Reduce the iloprost dose if symptomatic hypotension occurs.
What other medicines interact with Amantadine?
MediHelp also lists interactions of Amantadine with, for example, Ethanol, Memantine-donepezil, Metoclopramide. The full list is on the Amantadine page.
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