Drug interactions
Amantadine + Influenza virus vaccine quadrivalent cell-cultured
Severity: Minor
Amantadine and Influenza virus vaccine quadrivalent cell-cultured: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cell-cultured quadrivalent vaccine is inactivated, so amantadine's antiviral activity should not affect the immune response. No clinically meaningful interaction is expected.
What this interaction means in plain words
Amantadine and Influenza virus vaccine quadrivalent cell-cultured have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established mechanism; an inactivated vaccine does not depend on viral replication.
What to do
No action needed; the vaccine can be given during amantadine therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amantadine
- Amantadine + Ethanol Major
- Amantadine + Memantine-donepezil Major
- Amantadine + Metoclopramide Major
- Amantadine + Metoclopramide intranasal Major
- Amantadine + Amifampridine Moderate
- Amantadine + Amisulpride Moderate
Frequently asked questions
Can I take Amantadine with Influenza virus vaccine quadrivalent cell-cultured?
MediHelp rates the interaction as minor. Amantadine and Influenza virus vaccine quadrivalent cell-cultured have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cell-cultured quadrivalent vaccine is inactivated, so amantadine's antiviral activity should not affect the immune response. No clinically meaningful interaction is expected.
How serious is the interaction between Amantadine and Influenza virus vaccine quadrivalent cell-cultured?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action needed; the vaccine can be given during amantadine therapy.
What other medicines interact with Amantadine?
MediHelp also lists interactions of Amantadine with, for example, Ethanol, Memantine-donepezil, Metoclopramide. The full list is on the Amantadine page.
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