Drug interactions
Amikacin + Peramivir
Severity: Minor
Amikacin and Peramivir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Peramivir is cleared by the kidneys, and amikacin can reduce renal function, which may raise peramivir exposure. The clinical consequence is modest, but renal function matters for both drugs.
What this interaction means in plain words
Amikacin and Peramivir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible reduced renal clearance of peramivir through aminoglycoside-induced nephrotoxicity.
What to do
Monitor renal function and adjust peramivir dose to creatinine clearance if function declines.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amikacin
- Amikacin + Cidofovir Contraindicated
- Adefovir + Amikacin Major
- Amikacin + Amphotericin b Major
- Amikacin + Amphotericin b deoxycholate Major
- Amikacin + Atracurium Major
- Amikacin + Bacitracin Major
Frequently asked questions
Can I take Amikacin with Peramivir?
MediHelp rates the interaction as minor. Amikacin and Peramivir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Peramivir is cleared by the kidneys, and amikacin can reduce renal function, which may raise peramivir exposure. The clinical consequence is modest, but renal function matters for both drugs.
How serious is the interaction between Amikacin and Peramivir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and adjust peramivir dose to creatinine clearance if function declines.
What other medicines interact with Amikacin?
MediHelp also lists interactions of Amikacin with, for example, Cidofovir, Adefovir, Amphotericin b. The full list is on the Amikacin page.
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