Drug interactions
Aminohippurate + Hydrochlorothiazide-telmisartan
Severity: Minor
Aminohippurate and Hydrochlorothiazide-telmisartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazides are organic anions secreted by renal tubular transporters and may compete with aminohippurate. This can reduce its tubular secretion and make renal plasma flow measurements less accurate.
What this interaction means in plain words
Aminohippurate and Hydrochlorothiazide-telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Competition for renal organic anion tubular secretion.
What to do
Be aware of this when interpreting PAH clearance tests; consider holding the diuretic if the test requires precise results.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Frequently asked questions
Can I take Aminohippurate with Hydrochlorothiazide-telmisartan?
MediHelp rates the interaction as minor. Aminohippurate and Hydrochlorothiazide-telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazides are organic anions secreted by renal tubular transporters and may compete with aminohippurate. This can reduce its tubular secretion and make renal plasma flow measurements less accurate.
How serious is the interaction between Aminohippurate and Hydrochlorothiazide-telmisartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Be aware of this when interpreting PAH clearance tests; consider holding the diuretic if the test requires precise results.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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