Drug reference
hydrochlorothiazide-telmisartan
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Combination(CVS))
Mechanism of action
Telmisartan: Blocks binding of angiotensin II to type 1 angiotensin II receptors, causing a lowering in blood pressure; blocks vasoconstrictor and aldosterone-secreting effects of angiotensin II. HCT: inhibits sodium reabsorption in distal renal tubules, resulting in increased excretion of water and of sodium, potassium, and hydrogen ions
Common side effects
- Anorexia
- Back pain
- Urinary tract infection
- Diarrhea
Boxed warnings
- Discontinue as soon as possible when pregnancy is detected; affects renin-angiotensin system, causing oligohydramnios, which may result in fetal injury and/or death
Contraindications
- Hypersensitivity (anaphylaxis, angioedema) to drug components or sulfonamides Anuria Coadministration with aliskiren in patients with diabetes
Known interactions (2)
Related conditions
Frequently asked questions
What drug class is hydrochlorothiazide-telmisartan?
hydrochlorothiazide-telmisartan belongs to: Cardiovascular.
How does hydrochlorothiazide-telmisartan work?
Telmisartan: Blocks binding of angiotensin II to type 1 angiotensin II receptors, causing a lowering in blood pressure; blocks vasoconstrictor and aldosterone-secreting effects of angiotensin II. HCT: inhibits sodium reabsorption in distal renal tubules, resulting in increased excretion of water and of sodium, potassium, and hydrogen ions
What are the common side effects of hydrochlorothiazide-telmisartan?
Anorexia, Back pain, Urinary tract infection, Diarrhea
Which drugs interact with hydrochlorothiazide-telmisartan?
ramipril, isocarboxazid
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