Drug interactions
Aminohippurate + Meclofenamic acid
Severity: Minor
Aminohippurate and Meclofenamic acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aminohippurate is an organic anion used as a diagnostic agent to measure renal plasma flow and is secreted by renal tubular anion transporters. NSAIDs compete for this transport and can alter the test result, rather than causing a therapeutic effect.
What this interaction means in plain words
Aminohippurate and Meclofenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Competition for organic anion transporter-mediated renal tubular secretion.
What to do
Interpret renal plasma flow measurements with caution if the patient has taken an NSAID recently; consider holding the NSAID before the test.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Meclofenamic acid
- Ketorolac intranasal + Meclofenamic acid Contraindicated
- Ketorolac + Meclofenamic acid Contraindicated
- Aceclofenac + Meclofenamic acid Major
- Acemetacin + Meclofenamic acid Major
- Alteplase + Meclofenamic acid Major
- Amiloride + Meclofenamic acid Major
Frequently asked questions
Can I take Aminohippurate with Meclofenamic acid?
MediHelp rates the interaction as minor. Aminohippurate and Meclofenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aminohippurate is an organic anion used as a diagnostic agent to measure renal plasma flow and is secreted by renal tubular anion transporters. NSAIDs compete for this transport and can alter the test result, rather than causing a therapeutic effect.
How serious is the interaction between Aminohippurate and Meclofenamic acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Interpret renal plasma flow measurements with caution if the patient has taken an NSAID recently; consider holding the NSAID before the test.
What other medicines interact with Meclofenamic acid?
MediHelp also lists interactions of Meclofenamic acid with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meclofenamic acid page.
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