Drug interactions
Albuterol + Amiodarone
Severity: Moderate
Albuterol and Amiodarone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Albuterol can cause tachycardia, hypokalemia and QT changes, and amiodarone prolongs the QT interval. Together they may raise the risk of ventricular arrhythmia, mainly with high or systemic albuterol doses.
What this interaction means in plain words
Albuterol and Amiodarone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta2-agonist-induced hypokalemia potentiating the effect.
What to do
Monitor serum potassium and ECG in patients needing frequent albuterol. Use the lowest effective dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amiodarone
- Amiodarone + Amisulpride Contraindicated
- Amiodarone + Arsenic trioxide Contraindicated
- Amiodarone + Dofetilide Contraindicated
- Amiodarone + Dronedarone Contraindicated
- Amiodarone + Droperidol Contraindicated
- Amiodarone + Eliglustat Contraindicated
Frequently asked questions
Can I take Albuterol with Amiodarone?
MediHelp rates the interaction as moderate. Albuterol and Amiodarone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Albuterol can cause tachycardia, hypokalemia and QT changes, and amiodarone prolongs the QT interval. Together they may raise the risk of ventricular arrhythmia, mainly with high or systemic albuterol doses.
How serious is the interaction between Albuterol and Amiodarone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and ECG in patients needing frequent albuterol. Use the lowest effective dose.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
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