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Drug interactions

Amlodipine-benazepril + Artemether / lumefantrine

Severity: Minor

Amlodipine-benazepril and Artemether / lumefantrine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Artemether is a weak CYP3A4 inducer and may slightly reduce amlodipine exposure. Because treatment courses are short, the clinical effect is likely small.

What this interaction means in plain words

Amlodipine-benazepril and Artemether / lumefantrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Weak CYP3A4 induction increases amlodipine metabolism.

What to do

No routine adjustment is needed. Check blood pressure if control appears reduced during or after the course.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Amlodipine-benazepril with Artemether / lumefantrine?

MediHelp rates the interaction as minor. Amlodipine-benazepril and Artemether / lumefantrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Artemether is a weak CYP3A4 inducer and may slightly reduce amlodipine exposure. Because treatment courses are short, the clinical effect is likely small.

How serious is the interaction between Amlodipine-benazepril and Artemether / lumefantrine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Check blood pressure if control appears reduced during or after the course.

What other medicines interact with Amlodipine-benazepril?

MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.

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