Drug reference
amlodipine-benazepril
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Combination(CVS))
Mechanism of action
Amlodipine: Ca channel blocker; inhibits the transmembrane influx of extracellular Ca ions across the membranes of myocardial cells and vascular smooth muscle cells. Benazepril: Competitively inhibits angiotensin-converting enzymes, resulting in decreased plasma angiotensin II concentrations;
Common side effects
- Dyspepsia
- Dizziness
- Fatigue
- Pulmonary edema
- Abdominal pain
- Peripheral edema
Boxed warnings
- Discontinue as soon as possible when pregnancy is detected; affects renin-angiotensin system, causing oligohydramnios, which may result in fetal injury and/or death
Contraindications
- Hypersensitivity History of angioedema with or without previous ACE inhibitor therapy Hereditary or idiopathic angioedema Coadministration of neprilysin inhibitors (eg, sacubitril) with ACE inhibitors may increase angioedema risk; do not administer ACE inhibitors within 36 hr of switching…
Known interactions (1)
- amlodipine-benazepril + dantrolene Moderate
Related conditions
Frequently asked questions
What drug class is amlodipine-benazepril?
amlodipine-benazepril belongs to: Cardiovascular.
How does amlodipine-benazepril work?
Amlodipine: Ca channel blocker; inhibits the transmembrane influx of extracellular Ca ions across the membranes of myocardial cells and vascular smooth muscle cells. Benazepril: Competitively inhibits angiotensin-converting enzymes, resulting in decreased plasma angiotensin II concentrations;
What are the common side effects of amlodipine-benazepril?
Dyspepsia, Dizziness, Fatigue, Pulmonary edema, Abdominal pain, Peripheral edema
Which drugs interact with amlodipine-benazepril?
dantrolene
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