Drug interactions
Amlodipine-benazepril + Bisoprolol
Severity: Moderate
Amlodipine-benazepril and Bisoprolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bisoprolol with amlodipine and benazepril gives additive blood pressure reduction. This is often intentional, but excessive hypotension or bradycardia can occur.
What this interaction means in plain words
Amlodipine-benazepril and Bisoprolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-benazepril belongs to Cardiovascular; Bisoprolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects of beta-blockade, calcium channel blockade and ACE inhibition.
What to do
Monitor blood pressure and heart rate during initiation and titration. Adjust doses if symptoms of hypotension or bradycardia appear.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Bisoprolol
Frequently asked questions
Can I take Amlodipine-benazepril with Bisoprolol?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Bisoprolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bisoprolol with amlodipine and benazepril gives additive blood pressure reduction. This is often intentional, but excessive hypotension or bradycardia can occur.
How serious is the interaction between Amlodipine-benazepril and Bisoprolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate during initiation and titration. Adjust doses if symptoms of hypotension or bradycardia appear.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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