Drug interactions
Amlodipine-benazepril + Calcium chloride
Severity: Minor
Amlodipine-benazepril and Calcium chloride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Intravenous calcium can reverse the effects of calcium channel blockers and is used as an antidote in overdose. At therapeutic doses of oral amlodipine, intravenous calcium chloride may transiently reduce its antihypertensive effect.
What this interaction means in plain words
Amlodipine-benazepril and Calcium chloride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Raised extracellular calcium overcomes L-type calcium channel blockade.
What to do
No action is needed for routine use; monitor blood pressure and heart rate after IV calcium administration.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Frequently asked questions
Can I take Amlodipine-benazepril with Calcium chloride?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Calcium chloride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Intravenous calcium can reverse the effects of calcium channel blockers and is used as an antidote in overdose. At therapeutic doses of oral amlodipine, intravenous calcium chloride may transiently reduce its antihypertensive effect.
How serious is the interaction between Amlodipine-benazepril and Calcium chloride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed for routine use; monitor blood pressure and heart rate after IV calcium administration.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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