Drug interactions
Amlodipine-benazepril + Choline magnesium trisalicylate
Severity: Moderate
Amlodipine-benazepril and Choline magnesium trisalicylate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This salicylate may attenuate the antihypertensive action of benazepril and, at anti-inflammatory doses, may worsen renal function especially in dehydrated or older patients.
What this interaction means in plain words
Amlodipine-benazepril and Choline magnesium trisalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Prostaglandin synthesis inhibition reduces renal perfusion and opposes ACE inhibitor vasodilation.
What to do
Monitor blood pressure and serum creatinine, maintain hydration, and use the lowest effective salicylate dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Frequently asked questions
Can I take Amlodipine-benazepril with Choline magnesium trisalicylate?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Choline magnesium trisalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. This salicylate may attenuate the antihypertensive action of benazepril and, at anti-inflammatory doses, may worsen renal function especially in dehydrated or older patients.
How serious is the interaction between Amlodipine-benazepril and Choline magnesium trisalicylate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and serum creatinine, maintain hydration, and use the lowest effective salicylate dose.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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