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Drug interactions

Amlodipine-benazepril + Creatine

Severity: Minor

Amlodipine-benazepril and Creatine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Creatine supplementation may affect renal function markers and has been theorized to add to renal stress with ACE inhibitors. Evidence of real harm is limited.

What this interaction means in plain words

Amlodipine-benazepril and Creatine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical additive renal effects; mechanism not established.

What to do

Monitor serum creatinine and renal function in patients taking both, interpreting creatinine rises with creatine use in mind.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Amlodipine-benazepril with Creatine?

MediHelp rates the interaction as minor. Amlodipine-benazepril and Creatine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Creatine supplementation may affect renal function markers and has been theorized to add to renal stress with ACE inhibitors. Evidence of real harm is limited.

How serious is the interaction between Amlodipine-benazepril and Creatine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and renal function in patients taking both, interpreting creatinine rises with creatine use in mind.

What other medicines interact with Amlodipine-benazepril?

MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.

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