Drug interactions
Amlodipine-benazepril + Dextroamphetamine
Severity: Moderate
Amlodipine-benazepril and Dextroamphetamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dextroamphetamine raises blood pressure and heart rate through sympathomimetic action, which can counteract the effect of antihypertensives. Blood pressure control may be worse in treated hypertensive patients.
What this interaction means in plain words
Amlodipine-benazepril and Dextroamphetamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-benazepril belongs to Cardiovascular; Dextroamphetamine belongs to Central Nervous System.
Why it happens
Sympathomimetic release of catecholamines causes vasoconstriction that opposes the antihypertensive effect.
What to do
Monitor blood pressure regularly after starting or changing the stimulant dose and adjust antihypertensive therapy if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Amlodipine-benazepril with Dextroamphetamine?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Dextroamphetamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dextroamphetamine raises blood pressure and heart rate through sympathomimetic action, which can counteract the effect of antihypertensives. Blood pressure control may be worse in treated hypertensive patients.
How serious is the interaction between Amlodipine-benazepril and Dextroamphetamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure regularly after starting or changing the stimulant dose and adjust antihypertensive therapy if needed.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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