Drug interactions
Amlodipine-benazepril + Exenatide injectable
Severity: Minor
Amlodipine-benazepril and Exenatide injectable: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors may improve insulin sensitivity and enhance glucose lowering in patients on antidiabetic drugs. Combined with exenatide, this could modestly raise the risk of hypoglycemia, particularly with a sulfonylurea or insulin.
What this interaction means in plain words
Amlodipine-benazepril and Exenatide injectable have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
ACE inhibitors may improve insulin sensitivity, adding to the glucose-lowering effect of exenatide.
What to do
Monitor blood glucose when starting benazepril, especially in the first weeks. Reduce the dose of any concurrent sulfonylurea or insulin if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Frequently asked questions
Can I take Amlodipine-benazepril with Exenatide injectable?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Exenatide injectable have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. ACE inhibitors may improve insulin sensitivity and enhance glucose lowering in patients on antidiabetic drugs. Combined with exenatide, this could modestly raise the risk of hypoglycemia, particularly with a sulfonylurea or insulin.
How serious is the interaction between Amlodipine-benazepril and Exenatide injectable?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting benazepril, especially in the first weeks. Reduce the dose of any concurrent sulfonylurea or insulin if hypoglycemia occurs.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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