Drug interactions
Amlodipine-benazepril + Moxisylyte
Severity: Moderate
Amlodipine-benazepril and Moxisylyte: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxisylyte is an alpha-adrenergic blocker with vasodilating properties. It may add to the blood pressure lowering effects of amlodipine and benazepril, causing postural hypotension.
What this interaction means in plain words
Amlodipine-benazepril and Moxisylyte can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive vasodilation and hypotension from alpha blockade plus calcium channel blockade and ACE inhibition.
What to do
Monitor blood pressure and orthostatic symptoms when starting moxisylyte. Reduce the antihypertensive dose if symptomatic hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Frequently asked questions
Can I take Amlodipine-benazepril with Moxisylyte?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Moxisylyte can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Moxisylyte is an alpha-adrenergic blocker with vasodilating properties. It may add to the blood pressure lowering effects of amlodipine and benazepril, causing postural hypotension.
How serious is the interaction between Amlodipine-benazepril and Moxisylyte?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and orthostatic symptoms when starting moxisylyte. Reduce the antihypertensive dose if symptomatic hypotension occurs.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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