Drug interactions
Amlodipine-benazepril + Nitric oxide gas
Severity: Minor
Amlodipine-benazepril and Nitric oxide gas: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inhaled nitric oxide is a pulmonary vasodilator with some systemic effect. Antihypertensive agents may theoretically increase the risk of hypotension, though inhaled nitric oxide is rapidly inactivated and systemic effects are usually small.
What this interaction means in plain words
Amlodipine-benazepril and Nitric oxide gas have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive vasodilatory and hypotensive effects.
What to do
Monitor blood pressure continuously during nitric oxide therapy in patients on antihypertensives. Hold or reduce oral antihypertensives if hypotension develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Frequently asked questions
Can I take Amlodipine-benazepril with Nitric oxide gas?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Nitric oxide gas have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Inhaled nitric oxide is a pulmonary vasodilator with some systemic effect. Antihypertensive agents may theoretically increase the risk of hypotension, though inhaled nitric oxide is rapidly inactivated and systemic effects are usually small.
How serious is the interaction between Amlodipine-benazepril and Nitric oxide gas?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure continuously during nitric oxide therapy in patients on antihypertensives. Hold or reduce oral antihypertensives if hypotension develops.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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