Drug interactions
Amlodipine-benazepril + Remifentanil
Severity: Minor
Amlodipine-benazepril and Remifentanil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Remifentanil can cause hypotension and bradycardia, particularly during anesthesia. ACE inhibitors and calcium channel blockers may deepen the blood pressure drop.
What this interaction means in plain words
Amlodipine-benazepril and Remifentanil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-benazepril belongs to Cardiovascular; Remifentanil belongs to Musculoskeletal.
Why it happens
Additive pharmacodynamic hypotension from opioid-induced vasodilation and bradycardia combined with antihypertensive effects.
What to do
Monitor blood pressure continuously during remifentanil use. Treat hypotension with fluids or vasopressors and consider timing of antihypertensive doses before surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Remifentanil
- Alvimopan + Remifentanil Contraindicated
- Isocarboxazid + Remifentanil Contraindicated
- Olanzapine / samidorphan + Remifentanil Contraindicated
- Phenelzine + Remifentanil Contraindicated
- Benzhydrocodone / acetaminophen + Remifentanil Major
- Brexanolone + Remifentanil Major
Frequently asked questions
Can I take Amlodipine-benazepril with Remifentanil?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Remifentanil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Remifentanil can cause hypotension and bradycardia, particularly during anesthesia. ACE inhibitors and calcium channel blockers may deepen the blood pressure drop.
How serious is the interaction between Amlodipine-benazepril and Remifentanil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure continuously during remifentanil use. Treat hypotension with fluids or vasopressors and consider timing of antihypertensive doses before surgery.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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