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Drug interactions

Amlodipine-benazepril + Shepherd's purse

Severity: Minor

Amlodipine-benazepril and Shepherd's purse: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Shepherd's purse has been reported to affect blood pressure in animal studies, and use is poorly documented in humans. It might interfere with blood pressure control, but the evidence is theoretical.

What this interaction means in plain words

Amlodipine-benazepril and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Not established; theoretical effect on blood pressure from herbal constituents.

What to do

Advise patients to avoid shepherd's purse supplements while on antihypertensives. Check blood pressure if use is discovered.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Amlodipine-benazepril with Shepherd's purse?

MediHelp rates the interaction as minor. Amlodipine-benazepril and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shepherd's purse has been reported to affect blood pressure in animal studies, and use is poorly documented in humans. It might interfere with blood pressure control, but the evidence is theoretical.

How serious is the interaction between Amlodipine-benazepril and Shepherd's purse?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid shepherd's purse supplements while on antihypertensives. Check blood pressure if use is discovered.

What other medicines interact with Amlodipine-benazepril?

MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.

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