Drug interactions
Amlodipine-benazepril + Sodium sulfate / ?magnesium sulfate / potassium chloride
Severity: Minor
Amlodipine-benazepril and Sodium sulfate / ?magnesium sulfate / potassium chloride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This is a bowel preparation containing sulfate salts and potassium. Calcium channel blockers can add to hypotension or neuromuscular effects when magnesium is raised, and bowel prep fluid loss can worsen hypotension and electrolyte disturbance with an ACE inhibitor.
What this interaction means in plain words
Amlodipine-benazepril and Sodium sulfate / ?magnesium sulfate / potassium chloride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Magnesium has calcium-antagonist and vasodilating effects, and volume depletion adds to the antihypertensive effects.
What to do
Ensure adequate hydration during bowel preparation and consider holding benazepril on the day of preparation in patients prone to volume depletion. Monitor blood pressure and electrolytes in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Frequently asked questions
Can I take Amlodipine-benazepril with Sodium sulfate / ?magnesium sulfate / potassium chloride?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Sodium sulfate / ?magnesium sulfate / potassium chloride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. This is a bowel preparation containing sulfate salts and potassium. Calcium channel blockers can add to hypotension or neuromuscular effects when magnesium is raised, and bowel prep fluid loss can worsen hypotension and electrolyte disturbance with an ACE inhibitor.
How serious is the interaction between Amlodipine-benazepril and Sodium sulfate / ?magnesium sulfate / potassium chloride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ensure adequate hydration during bowel preparation and consider holding benazepril on the day of preparation in patients prone to volume depletion. Monitor blood pressure and electrolytes in patients with renal impairment.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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