Drug interactions
Amlodipine-benazepril + Synthetic human angiotensin ii
Severity: Moderate
Amlodipine-benazepril and Synthetic human angiotensin ii: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin II is a vasopressor used in vasodilatory shock. ACE inhibitor therapy can alter the pressor response, with reports of increased sensitivity to angiotensin II and greater blood pressure rise, while amlodipine may offset it.
What this interaction means in plain words
Amlodipine-benazepril and Synthetic human angiotensin ii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
ACE inhibition reduces endogenous angiotensin II generation, which can increase the pressor response to exogenous angiotensin II.
What to do
Titrate angiotensin II carefully with continuous blood pressure monitoring in patients taking an ACE inhibitor. Expect that lower doses may be needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Frequently asked questions
Can I take Amlodipine-benazepril with Synthetic human angiotensin ii?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Synthetic human angiotensin ii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Angiotensin II is a vasopressor used in vasodilatory shock. ACE inhibitor therapy can alter the pressor response, with reports of increased sensitivity to angiotensin II and greater blood pressure rise, while amlodipine may offset it.
How serious is the interaction between Amlodipine-benazepril and Synthetic human angiotensin ii?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate angiotensin II carefully with continuous blood pressure monitoring in patients taking an ACE inhibitor. Expect that lower doses may be needed.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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