Drug interactions
Amlodipine-valsartan + Atracurium
Severity: Minor
Amlodipine-valsartan and Atracurium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers may potentiate nondepolarizing neuromuscular blockers, prolonging or deepening blockade. The effect is mostly relevant in the perioperative setting.
What this interaction means in plain words
Amlodipine-valsartan and Atracurium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-valsartan belongs to Cardiovascular; Atracurium belongs to Musculoskeletal.
Why it happens
Calcium channel blockade may reduce presynaptic acetylcholine release, adding to neuromuscular blockade.
What to do
Monitor neuromuscular function with a train-of-four monitor and titrate the blocker dose accordingly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-valsartan
- Aliskiren + Amlodipine-valsartan Contraindicated
- Amlodipine-valsartan + Sparsentan Contraindicated
- Aldesleukin + Amlodipine-valsartan Major
- Amifostine + Amlodipine-valsartan Major
- Amiloride + Amlodipine-valsartan Major
- Amlodipine-valsartan + Benazepril Major
Other interactions of Atracurium
Frequently asked questions
Can I take Amlodipine-valsartan with Atracurium?
MediHelp rates the interaction as minor. Amlodipine-valsartan and Atracurium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers may potentiate nondepolarizing neuromuscular blockers, prolonging or deepening blockade. The effect is mostly relevant in the perioperative setting.
How serious is the interaction between Amlodipine-valsartan and Atracurium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor neuromuscular function with a train-of-four monitor and titrate the blocker dose accordingly.
What other medicines interact with Amlodipine-valsartan?
MediHelp also lists interactions of Amlodipine-valsartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Amlodipine-valsartan page.
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