Drug interactions
Amlodipine-valsartan + Calcium chloride
Severity: Minor
Amlodipine-valsartan and Calcium chloride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Intravenous calcium chloride can reverse the effects of calcium channel blockers and is used as an antidote in amlodipine overdose. In routine therapy, the effect on blood pressure control is temporary and generally not important.
What this interaction means in plain words
Amlodipine-valsartan and Calcium chloride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Raised extracellular calcium concentration pharmacologically antagonizes L-type calcium channel blockade.
What to do
No action is needed for routine use; expect reduced amlodipine effect after parenteral calcium and monitor blood pressure and heart rate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-valsartan
- Aliskiren + Amlodipine-valsartan Contraindicated
- Amlodipine-valsartan + Sparsentan Contraindicated
- Aldesleukin + Amlodipine-valsartan Major
- Amifostine + Amlodipine-valsartan Major
- Amiloride + Amlodipine-valsartan Major
- Amlodipine-valsartan + Benazepril Major
Frequently asked questions
Can I take Amlodipine-valsartan with Calcium chloride?
MediHelp rates the interaction as minor. Amlodipine-valsartan and Calcium chloride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Intravenous calcium chloride can reverse the effects of calcium channel blockers and is used as an antidote in amlodipine overdose. In routine therapy, the effect on blood pressure control is temporary and generally not important.
How serious is the interaction between Amlodipine-valsartan and Calcium chloride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed for routine use; expect reduced amlodipine effect after parenteral calcium and monitor blood pressure and heart rate.
What other medicines interact with Amlodipine-valsartan?
MediHelp also lists interactions of Amlodipine-valsartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Amlodipine-valsartan page.
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