Drug interactions
Amlodipine-valsartan + Trimagnesium
Severity: Minor
Amlodipine-valsartan and Trimagnesium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Magnesium has mild calcium-antagonist properties and can add to the vasodilation of amlodipine. Excess magnesium, particularly with high doses or renal impairment, may lead to hypotension or muscle weakness. At usual oral supplement doses the effect is generally small.
What this interaction means in plain words
Amlodipine-valsartan and Trimagnesium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive calcium-channel antagonism and vasodilation from magnesium with amlodipine.
What to do
Monitor blood pressure if large or parenteral magnesium doses are used. Take extra care in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-valsartan
- Aliskiren + Amlodipine-valsartan Contraindicated
- Amlodipine-valsartan + Sparsentan Contraindicated
- Aldesleukin + Amlodipine-valsartan Major
- Amifostine + Amlodipine-valsartan Major
- Amiloride + Amlodipine-valsartan Major
- Amlodipine-valsartan + Benazepril Major
Frequently asked questions
Can I take Amlodipine-valsartan with Trimagnesium?
MediHelp rates the interaction as minor. Amlodipine-valsartan and Trimagnesium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Magnesium has mild calcium-antagonist properties and can add to the vasodilation of amlodipine. Excess magnesium, particularly with high doses or renal impairment, may lead to hypotension or muscle weakness. At usual oral supplement doses the effect is generally small.
How serious is the interaction between Amlodipine-valsartan and Trimagnesium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if large or parenteral magnesium doses are used. Take extra care in patients with renal impairment.
What other medicines interact with Amlodipine-valsartan?
MediHelp also lists interactions of Amlodipine-valsartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Amlodipine-valsartan page.
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