Drug interactions
Anakinra + Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine
Severity: Minor
Anakinra and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This is a non-live combination vaccine and can be given with anakinra. A slightly reduced antibody response is theoretically possible.
What this interaction means in plain words
Anakinra and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
IL-1 blockade may mildly attenuate immune responses to vaccine antigens.
What to do
Immunize on schedule and do not stop anakinra; check the response if protection is critical.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Anakinra
- Anakinra + Bcg vaccine live Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine live Contraindicated
- Anakinra + Measles mumps rubella and varicella vaccine live Contraindicated
- Anakinra + Measles vaccine Contraindicated
- Abatacept + Anakinra Major
Frequently asked questions
Can I take Anakinra with Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine?
MediHelp rates the interaction as minor. Anakinra and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. This is a non-live combination vaccine and can be given with anakinra. A slightly reduced antibody response is theoretically possible.
How serious is the interaction between Anakinra and Diphtheria and tetanus toxoids / acellular pertussis / poliovirus inactivated vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Immunize on schedule and do not stop anakinra; check the response if protection is critical.
What other medicines interact with Anakinra?
MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.
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