Drug interactions
Anakinra + Echinacea
Severity: Minor
Anakinra and Echinacea: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Echinacea is claimed to stimulate immune function, which in theory could oppose the effect of anakinra on inflammation. The clinical significance is uncertain and not well documented.
What this interaction means in plain words
Anakinra and Echinacea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Anakinra belongs to Musculoskeletal; Echinacea belongs to Gastrointestinal Tract.
Why it happens
Theoretical pharmacodynamic opposition between immune stimulation by echinacea and IL-1 blockade; not established.
What to do
Advise patients to avoid echinacea supplements while on anakinra, and monitor disease control if they are used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Anakinra
- Anakinra + Bcg vaccine live Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine live Contraindicated
- Anakinra + Measles mumps rubella and varicella vaccine live Contraindicated
- Anakinra + Measles vaccine Contraindicated
- Abatacept + Anakinra Major
Other interactions of Echinacea
- Alefacept + Echinacea Moderate
- Antithymocyte globulin equine + Echinacea Moderate
- Antithymocyte globulin rabbit + Echinacea Moderate
- Azathioprine + Echinacea Moderate
- Basiliximab + Echinacea Moderate
- Cyclosporin + Echinacea Moderate
Frequently asked questions
Can I take Anakinra with Echinacea?
MediHelp rates the interaction as minor. Anakinra and Echinacea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Echinacea is claimed to stimulate immune function, which in theory could oppose the effect of anakinra on inflammation. The clinical significance is uncertain and not well documented.
How serious is the interaction between Anakinra and Echinacea?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid echinacea supplements while on anakinra, and monitor disease control if they are used.
What other medicines interact with Anakinra?
MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.
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