Drug interactions
Anakinra + Hepatitis a / typhoid vaccine
Severity: Minor
Anakinra and Hepatitis a / typhoid vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This combination contains inactivated hepatitis A and Vi typhoid antigens and is non-live. Anakinra may slightly reduce the response, but vaccination remains appropriate.
What this interaction means in plain words
Anakinra and Hepatitis a / typhoid vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
IL-1 receptor blockade may mildly dampen vaccine immune responses.
What to do
Vaccinate at least 2 weeks before travel, ideally before beginning anakinra; maintain food and water precautions.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Anakinra
- Anakinra + Bcg vaccine live Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine live Contraindicated
- Anakinra + Measles mumps rubella and varicella vaccine live Contraindicated
- Anakinra + Measles vaccine Contraindicated
- Abatacept + Anakinra Major
Frequently asked questions
Can I take Anakinra with Hepatitis a / typhoid vaccine?
MediHelp rates the interaction as minor. Anakinra and Hepatitis a / typhoid vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. This combination contains inactivated hepatitis A and Vi typhoid antigens and is non-live. Anakinra may slightly reduce the response, but vaccination remains appropriate.
How serious is the interaction between Anakinra and Hepatitis a / typhoid vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate at least 2 weeks before travel, ideally before beginning anakinra; maintain food and water precautions.
What other medicines interact with Anakinra?
MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.
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