Drug interactions
Anakinra + Hepatitis b vaccine
Severity: Minor
Anakinra and Hepatitis b vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hepatitis B vaccine is non-live and safe with anakinra, though the antibody response may be lower in immunosuppressed patients.
What this interaction means in plain words
Anakinra and Hepatitis b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
IL-1 blockade may modestly attenuate vaccine-induced antibody production.
What to do
Complete the series and check anti-HBs titres after vaccination, giving a booster if the level is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Anakinra
- Anakinra + Bcg vaccine live Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine live Contraindicated
- Anakinra + Measles mumps rubella and varicella vaccine live Contraindicated
- Anakinra + Measles vaccine Contraindicated
- Abatacept + Anakinra Major
Frequently asked questions
Can I take Anakinra with Hepatitis b vaccine?
MediHelp rates the interaction as minor. Anakinra and Hepatitis b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hepatitis B vaccine is non-live and safe with anakinra, though the antibody response may be lower in immunosuppressed patients.
How serious is the interaction between Anakinra and Hepatitis b vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete the series and check anti-HBs titres after vaccination, giving a booster if the level is inadequate.
What other medicines interact with Anakinra?
MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.
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