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Drug interactions

Anakinra + Influenza virus vaccine quadrivalent recombinant

Severity: Minor

Anakinra and Influenza virus vaccine quadrivalent recombinant: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Anakinra may modestly reduce the immune response to vaccination, though data show responses are generally preserved. The recombinant vaccine is non-live and can be given safely.

What this interaction means in plain words

Anakinra and Influenza virus vaccine quadrivalent recombinant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

IL-1 blockade may slightly dampen vaccine-induced immune responses.

What to do

Give the annual influenza vaccine as recommended; no dose change or interruption of anakinra is generally needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Anakinra with Influenza virus vaccine quadrivalent recombinant?

MediHelp rates the interaction as minor. Anakinra and Influenza virus vaccine quadrivalent recombinant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Anakinra may modestly reduce the immune response to vaccination, though data show responses are generally preserved. The recombinant vaccine is non-live and can be given safely.

How serious is the interaction between Anakinra and Influenza virus vaccine quadrivalent recombinant?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the annual influenza vaccine as recommended; no dose change or interruption of anakinra is generally needed.

What other medicines interact with Anakinra?

MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.

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