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Drug interactions

Anakinra + Influenza virus vaccine quadrivalent

Severity: Minor

Anakinra and Influenza virus vaccine quadrivalent: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

The inactivated influenza vaccine can be used with anakinra, and annual vaccination is recommended in this population. The antibody response may be slightly reduced.

What this interaction means in plain words

Anakinra and Influenza virus vaccine quadrivalent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

IL-1 receptor blockade may modestly reduce vaccine-induced immunity.

What to do

Give the inactivated vaccine annually; do not delay or withhold it because of anakinra.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Anakinra with Influenza virus vaccine quadrivalent?

MediHelp rates the interaction as minor. Anakinra and Influenza virus vaccine quadrivalent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The inactivated influenza vaccine can be used with anakinra, and annual vaccination is recommended in this population. The antibody response may be slightly reduced.

How serious is the interaction between Anakinra and Influenza virus vaccine quadrivalent?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the inactivated vaccine annually; do not delay or withhold it because of anakinra.

What other medicines interact with Anakinra?

MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.

Full monographs, dosing and an interaction checker in the MediHelp app

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