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Drug interactions

Anakinra + Influenza virus vaccine trivalent adjuvanted

Severity: Minor

Anakinra and Influenza virus vaccine trivalent adjuvanted: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Immunosuppressants can lower antibody responses to inactivated influenza vaccines. The vaccine remains safe and protective benefit is still expected, so the vaccine should not be withheld.

What this interaction means in plain words

Anakinra and Influenza virus vaccine trivalent adjuvanted have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

IL-1 blockade may modestly blunt the immune response to vaccine antigens.

What to do

Vaccinate as recommended each season; no change to anakinra is needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Anakinra with Influenza virus vaccine trivalent adjuvanted?

MediHelp rates the interaction as minor. Anakinra and Influenza virus vaccine trivalent adjuvanted have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Immunosuppressants can lower antibody responses to inactivated influenza vaccines. The vaccine remains safe and protective benefit is still expected, so the vaccine should not be withheld.

How serious is the interaction between Anakinra and Influenza virus vaccine trivalent adjuvanted?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate as recommended each season; no change to anakinra is needed.

What other medicines interact with Anakinra?

MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.

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