Drug interactions
Anakinra + Pneumococcal vaccine heptavalent
Severity: Minor
Anakinra and Pneumococcal vaccine heptavalent: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The conjugate pneumococcal vaccine is non-live and can be given with anakinra. A slightly weaker antibody response is possible, but vaccination is recommended because of the higher infection risk.
What this interaction means in plain words
Anakinra and Pneumococcal vaccine heptavalent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
IL-1 receptor blockade may modestly reduce vaccine-induced antibody responses.
What to do
Vaccinate per guidelines, ideally before or early in anakinra therapy, and do not interrupt treatment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Anakinra
- Anakinra + Bcg vaccine live Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine live Contraindicated
- Anakinra + Measles mumps rubella and varicella vaccine live Contraindicated
- Anakinra + Measles vaccine Contraindicated
- Abatacept + Anakinra Major
Frequently asked questions
Can I take Anakinra with Pneumococcal vaccine heptavalent?
MediHelp rates the interaction as minor. Anakinra and Pneumococcal vaccine heptavalent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The conjugate pneumococcal vaccine is non-live and can be given with anakinra. A slightly weaker antibody response is possible, but vaccination is recommended because of the higher infection risk.
How serious is the interaction between Anakinra and Pneumococcal vaccine heptavalent?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate per guidelines, ideally before or early in anakinra therapy, and do not interrupt treatment.
What other medicines interact with Anakinra?
MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.
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