Drug interactions
Anakinra + Tetanus toxoid adsorbed or fluid
Severity: Minor
Anakinra and Tetanus toxoid adsorbed or fluid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetanus toxoid is non-live, so it can be given to patients on anakinra. The antibody response may be somewhat lower, but protection is generally still achieved.
What this interaction means in plain words
Anakinra and Tetanus toxoid adsorbed or fluid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Pharmacodynamic: IL-1 blockade may slightly attenuate vaccine antibody responses.
What to do
Give tetanus toxoid as scheduled, including for wound management. No change to anakinra is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Anakinra
- Anakinra + Bcg vaccine live Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine live Contraindicated
- Anakinra + Measles mumps rubella and varicella vaccine live Contraindicated
- Anakinra + Measles vaccine Contraindicated
- Abatacept + Anakinra Major
Frequently asked questions
Can I take Anakinra with Tetanus toxoid adsorbed or fluid?
MediHelp rates the interaction as minor. Anakinra and Tetanus toxoid adsorbed or fluid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tetanus toxoid is non-live, so it can be given to patients on anakinra. The antibody response may be somewhat lower, but protection is generally still achieved.
How serious is the interaction between Anakinra and Tetanus toxoid adsorbed or fluid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give tetanus toxoid as scheduled, including for wound management. No change to anakinra is needed.
What other medicines interact with Anakinra?
MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.
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