Drug interactions
Anthrax immune globulin + Measles mumps and rubella vaccine
Severity: Moderate
Anthrax immune globulin and Measles mumps and rubella vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Passively acquired antibodies in immune globulin products can neutralize live attenuated vaccine viruses, reducing replication and the immune response. This can leave the person inadequately protected despite vaccination.
What this interaction means in plain words
Anthrax immune globulin and Measles mumps and rubella vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Passive antibodies neutralize live vaccine viruses and blunt the active immune response.
What to do
Defer MMR vaccination for about 3 months after anthrax immune globulin; revaccinate if the vaccine was given shortly before or after the immune globulin.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicated
- Azathioprine + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
Frequently asked questions
Can I take Anthrax immune globulin with Measles mumps and rubella vaccine?
MediHelp rates the interaction as moderate. Anthrax immune globulin and Measles mumps and rubella vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Passively acquired antibodies in immune globulin products can neutralize live attenuated vaccine viruses, reducing replication and the immune response. This can leave the person inadequately protected despite vaccination.
How serious is the interaction between Anthrax immune globulin and Measles mumps and rubella vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Defer MMR vaccination for about 3 months after anthrax immune globulin; revaccinate if the vaccine was given shortly before or after the immune globulin.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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