Drug interactions
Anthrax vaccine adsorbed + Cyclosporin
Severity: Moderate
Anthrax vaccine adsorbed and Cyclosporin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cyclosporine suppresses T-cell function and may reduce the antibody response to anthrax vaccine adsorbed. Patients may have inadequate protection after vaccination during therapy.
What this interaction means in plain words
Anthrax vaccine adsorbed and Cyclosporin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Calcineurin inhibition suppresses T-cell-dependent immune responses to the vaccine.
What to do
Vaccinate at least 2 weeks before starting cyclosporine when feasible. If vaccinated during immunosuppression, consider revaccination once immune competence has returned.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contraindicated
- Aliskiren + Cyclosporin Contraindicated
- Bcg vaccine live + Cyclosporin Contraindicated
- Bosentan + Cyclosporin Contraindicated
- Cidofovir + Cyclosporin Contraindicated
- Cyclosporin + Dengue vaccine Contraindicated
Frequently asked questions
Can I take Anthrax vaccine adsorbed with Cyclosporin?
MediHelp rates the interaction as moderate. Anthrax vaccine adsorbed and Cyclosporin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclosporine suppresses T-cell function and may reduce the antibody response to anthrax vaccine adsorbed. Patients may have inadequate protection after vaccination during therapy.
How serious is the interaction between Anthrax vaccine adsorbed and Cyclosporin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate at least 2 weeks before starting cyclosporine when feasible. If vaccinated during immunosuppression, consider revaccination once immune competence has returned.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
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