Drug interactions
Anthrax vaccine + Basiliximab
Severity: Moderate
Anthrax vaccine and Basiliximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Basiliximab blocks IL-2-driven lymphocyte activation and may weaken the antibody response to anthrax vaccine. The vaccine is non-live, so there is no infection risk from it, but protection may be inadequate.
What this interaction means in plain words
Anthrax vaccine and Basiliximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Basiliximab blocks the IL-2 receptor (CD25) on activated T cells, impairing the immune response to vaccine antigens.
What to do
Give the vaccine at least before transplant or when immunosuppression is lowest if feasible; consider checking antibody response when protection is required.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Anthrax vaccine and Basiliximab, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Anthrax vaccine with Basiliximab?
MediHelp rates the interaction as moderate. Anthrax vaccine and Basiliximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Basiliximab blocks IL-2-driven lymphocyte activation and may weaken the antibody response to anthrax vaccine. The vaccine is non-live, so there is no infection risk from it, but protection may be inadequate.
How serious is the interaction between Anthrax vaccine and Basiliximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the vaccine at least before transplant or when immunosuppression is lowest if feasible; consider checking antibody response when protection is required.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
