Drug interactions
Antithrombin alfa + Dipyridamole
Severity: Moderate
Antithrombin alfa and Dipyridamole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dipyridamole inhibits platelet function and antithrombin enhances anticoagulation, so combined use may increase bleeding risk modestly.
What this interaction means in plain words
Antithrombin alfa and Dipyridamole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive effect of platelet inhibition and antithrombin-mediated anticoagulation.
What to do
Monitor coagulation parameters and bleeding signs while on both drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Frequently asked questions
Can I take Antithrombin alfa with Dipyridamole?
MediHelp rates the interaction as moderate. Antithrombin alfa and Dipyridamole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dipyridamole inhibits platelet function and antithrombin enhances anticoagulation, so combined use may increase bleeding risk modestly.
How serious is the interaction between Antithrombin alfa and Dipyridamole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor coagulation parameters and bleeding signs while on both drugs.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
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