Drug interactions
Arformoterol + Clozapine
Severity: Moderate
Arformoterol and Clozapine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs may prolong the QT interval and increase heart rate. Beta-agonist induced hypokalemia can add to arrhythmic risk.
What this interaction means in plain words
Arformoterol and Clozapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Clozapine belongs to Central Nervous System.
Why it happens
Additive QT prolongation, tachycardia and beta-agonist hypokalemia.
What to do
Monitor heart rate, potassium and consider ECG in patients with other QT risk factors. Correct electrolyte abnormalities.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Clozapine
- Clozapine + Deferiprone Contraindicated
- Clozapine + Irinotecan Contraindicated
- Clozapine + Pimozide Contraindicated
- Clozapine + Thioridazine Contraindicated
- Acalabrutinib + Clozapine Major
- Adagrasib + Clozapine Major
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Clozapine?
MediHelp rates the interaction as moderate. Arformoterol and Clozapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs may prolong the QT interval and increase heart rate. Beta-agonist induced hypokalemia can add to arrhythmic risk.
How serious is the interaction between Arformoterol and Clozapine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, potassium and consider ECG in patients with other QT risk factors. Correct electrolyte abnormalities.
What other medicines interact with Clozapine?
MediHelp also lists interactions of Clozapine with, for example, Deferiprone, Irinotecan, Pimozide. The full list is on the Clozapine page.
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