Drug interactions
Arformoterol + Deflazacort
Severity: Moderate
Arformoterol and Deflazacort: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Long-acting beta-2 agonists and corticosteroids can each lower serum potassium. Together they may cause hypokalemia, which is more likely with high doses or in acute illness and can promote arrhythmias.
What this interaction means in plain words
Arformoterol and Deflazacort can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Deflazacort belongs to Miscellaneous.
Why it happens
Additive potassium lowering via beta-2-mediated cellular uptake and corticosteroid-induced renal potassium loss.
What to do
Monitor serum potassium in patients with risk factors such as hypoxia, heart disease or other potassium-lowering drugs, and replace as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Deflazacort?
MediHelp rates the interaction as moderate. Arformoterol and Deflazacort can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Long-acting beta-2 agonists and corticosteroids can each lower serum potassium. Together they may cause hypokalemia, which is more likely with high doses or in acute illness and can promote arrhythmias.
How serious is the interaction between Arformoterol and Deflazacort?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients with risk factors such as hypoxia, heart disease or other potassium-lowering drugs, and replace as needed.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
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